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... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Peptide > Receptors, Growth Factor > Receptors, Nerve Growth Factor > Receptor, Ciliary Neurotrophic Factor > Leukemia Inhibitory Factor Receptor alpha Subunit
... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Receptors, Cell Surface > Receptors, Immunologic > Receptors, Cytokine > Receptors, OSM-LIF > Leukemia Inhibitory Factor Receptor alpha Subunit

Preferred term

Leukemia Inhibitory Factor Receptor alpha Subunit  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Antigen, CD118
  • Antigens, CD118
  • CD118 Antigen
  • CD118 Antigens
  • LIF Receptor alpha Subunit

Scope note

  • A receptor subunit that combines with CYTOKINE RECEPTOR GP130 to form the dual specificity receptor for LEUKEMIA INHIBITORY FACTOR and ONCOSTATIN M. The subunit is also a component of the CILIARY NEUROTROPHIC FACTOR RECEPTOR. Both membrane-bound and secreted isoforms of the receptor subunit exist due to ALTERNATIVE SPLICING of its mRNA. The secreted isoform is believed to act as an inhibitory receptor, while the membrane-bound form is a signaling receptor.

History note

  • 2007

In other languages

URI

http://www.yso.fi/onto/mesh/D053680

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