Concept information
Biological Factors
Intercellular Signaling Peptides and Proteins
Cytokines
Transforming Growth Factor beta
...
Proteins
Intercellular Signaling Peptides and Proteins
Cytokines
Transforming Growth Factor beta
...
Peptides
Intercellular Signaling Peptides and Proteins
Cytokines
Transforming Growth Factor beta
Biological Factors
Intercellular Signaling Peptides and Proteins
TGF-beta Superfamily Proteins
Transforming Growth Factor beta
Preferred term
Transforming Growth Factor beta2
Type
-
Topical Descriptor
Broader concept
Entry terms
- BSC 1 Cell Growth Inhibitor
- BSC-1 Cell Growth Inhibitor
- Cartilage Inducing Factor B
- Cartilage-Inducing Factor-B
- Glioblastoma Derived T Cell Suppressor Factor
- Glioblastoma-Derived T-Cell Suppressor Factor
- Polyergin
- Suppressor Factor, T-Cell, Glioblastoma-Derived
- TGF-beta-2
- TGF-beta2
Scope note
- A TGF-beta subtype that was originally identified as a GLIOBLASTOMA-derived factor which inhibits the antigen-dependent growth of both helper and CYTOTOXIC T LYMPHOCYTES. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta2 and TGF-beta2 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.
History note
- 2007(2000)
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D053781
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