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Concept information

Preferred term

Transforming Growth Factor beta3  

Type

  • Topical Descriptor

Entry terms

  • TGFB3
  • TGF beta 3
  • TGF beta3
  • TGF-beta-3
  • TGF-beta3

Scope note

  • A TGF-beta subtype that plays role in regulating epithelial-mesenchymal interaction during embryonic development. It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta3 and TGF-beta3 latency-associated peptide. The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor.

History note

  • 2007(2000)

In other languages

URI

http://www.yso.fi/onto/mesh/D053782

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