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Concept information

Preferred term

Granzymes  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Granzyme

Scope note

  • A family of serine endopeptidases found in the SECRETORY GRANULES of LEUKOCYTES such as CYTOTOXIC T-LYMPHOCYTES and NATURAL KILLER CELLS. When secreted into the intercellular space granzymes act to eliminate transformed and virus-infected host cells.

History note

  • 2007(1986)

In other languages

URI

http://www.yso.fi/onto/mesh/D053804

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