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Concept information

Preferred term

Leukemia, Large Granular Lymphocytic  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Aggressive Natural Killer Cell Leukemia
  • Aggressive NK Cell Leukemia
  • Large Granular Lymphocyte Leukemia
  • Leukemia, LGL
  • Leukemia, Lymphocytic, Large Granular
  • Leukemias, LGL
  • LGL Leukemia
  • LGL Leukemias
  • Lymphoproliferative Disease of Granular Lymphocytes
  • Lymphoproliferative Disease of Large Granular Lymphocytes

Scope note

  • A spectrum of disorders characterized by clonal expansions of the peripheral blood LYMPHOCYTE populations known as large granular lymphocytes which contain abundant cytoplasm and azurophilic granules. Subtypes develop from either CD3-negative NATURAL KILLER CELLS or CD3-positive T-CELLS. The clinical course of both subtypes can vary from spontaneous regression to progressive, malignant disease.

History note

  • 2008; use LEUKEMIA, LYMPHOCYTIC 1997-2007

URI

http://www.yso.fi/onto/mesh/D054066

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