Concept information
Preferred term
Agouti-Related Protein
Type
-
Topical Descriptor
Broader concept
Entry terms
- AGRP Protein
- AGRT Protein
Scope note
- A secreted protein of approximately 131 amino acids that is related to AGOUTI SIGNALING PROTEIN and is also an antagonist of MELANOCORTIN RECEPTOR activity. It is expressed primarily in the HYPOTHALAMUS and the ADRENAL GLAND. As a paracrine signaling molecule, AGRP is known to regulate food intake and body weight. Elevated AGRP has been associated with OBESITY.
History note
- 2008 (1997)
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D054369
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