Concept information
Amino Acids, Peptides, and Proteins
Proteins
Intracellular Signaling Peptides and Proteins
Protein Serine-Threonine Kinases
Preferred term
rho-Associated Kinases
Type
-
Topical Descriptor
Broader concept
Entry terms
- Coiled-Coil Kinase, rho-Associated
- Protein Kinases, ROCK
- rho Associated Coiled Coil Kinase
- rho-Associated Coiled-Coil Kinase
- rho Associated Kinase
- rho-Associated Kinase
- rho Kinase
- rho-Kinase
- ROCK Protein Kinases
- ROK Kinase
Scope note
- A group of intracellular-signaling serine threonine kinases that bind to RHO GTP-BINDING PROTEINS. They were originally found to mediate the effects of rhoA GTP-BINDING PROTEIN on the formation of STRESS FIBERS and FOCAL ADHESIONS. Rho-associated kinases have specificity for a variety of substrates including MYOSIN-LIGHT-CHAIN PHOSPHATASE and LIM KINASES.
History note
- 2008
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D054460
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