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Concept information

Preferred term

Protein Tyrosine Phosphatase, Non-Receptor Type 1  

Type

  • Topical Descriptor

Entry terms

  • Protein Tyrosine Phosphatase 1B
  • Protein Tyrosine Phosphatase HA2
  • Protein-Tyrosine Phosphatase HA2
  • PTPase 1B
  • PTPase HA2

Scope note

  • A subtype of non-receptor protein tyrosine phosphatases that includes two distinctive targeting motifs; an N-terminal motif specific for the INSULIN RECEPTOR, and a C-terminal motif specific for the SH3 domain containing proteins. This subtype includes a hydrophobic domain which localizes it to the ENDOPLASMIC RETICULUM.

History note

  • 2008

URI

http://www.yso.fi/onto/mesh/D054562

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