Concept information
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Proteins
Intracellular Signaling Peptides and Proteins
Protein Tyrosine Phosphatases
Protein Tyrosine Phosphatases, Non-Receptor
Preferred term
Protein Tyrosine Phosphatase, Non-Receptor Type 1
Type
-
Topical Descriptor
Broader concept
Entry terms
- Protein Tyrosine Phosphatase 1B
- Protein Tyrosine Phosphatase HA2
- Protein-Tyrosine Phosphatase HA2
- PTPase 1B
- PTPase HA2
Scope note
- A subtype of non-receptor protein tyrosine phosphatases that includes two distinctive targeting motifs; an N-terminal motif specific for the INSULIN RECEPTOR, and a C-terminal motif specific for the SH3 domain containing proteins. This subtype includes a hydrophobic domain which localizes it to the ENDOPLASMIC RETICULUM.
History note
- 2008
In other languages
URI
http://www.yso.fi/onto/mesh/D054562
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