Concept information
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Proteins
Intracellular Signaling Peptides and Proteins
Protein Tyrosine Phosphatases
Protein Tyrosine Phosphatases, Non-Receptor
Preferred term
Protein Tyrosine Phosphatase, Non-Receptor Type 2
Type
-
Topical Descriptor
Broader concept
Entry terms
- T Cell Protein Tyrosine Phosphatase
- T-Cell Protein Tyrosine Phosphatase
- TC-PTP
- TCPTP Enzyme
Scope note
- A subtype of non-receptor protein tyrosine phosphatase that is closely-related to PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1. Alternative splicing of the mRNA for this phosphatase results in the production at two gene products, one of which includes a C-terminal nuclear localization domain that may be involved in the transport of the protein to the CELL NUCLEUS. Although initially referred to as T-cell protein tyrosine phosphatase the expression of this subtype occurs widely.
History note
- 2008(1994)
In other languages
URI
http://www.yso.fi/onto/mesh/D054578
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