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... > Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Protein Tyrosine Phosphatases > Protein Tyrosine Phosphatases, Non-Receptor > Protein Tyrosine Phosphatase, Non-Receptor Type 12
... > Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Protein Tyrosine Phosphatases > Protein Tyrosine Phosphatases, Non-Receptor > Protein Tyrosine Phosphatase, Non-Receptor Type 12
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Esterases > Phosphoric Monoester Hydrolases > Protein Tyrosine Phosphatases > Protein Tyrosine Phosphatases, Non-Receptor > Protein Tyrosine Phosphatase, Non-Receptor Type 12

Preferred term

Protein Tyrosine Phosphatase, Non-Receptor Type 12  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • PEP Protein Tyrosine Phosphatase
  • PEP PTPase
  • PEST Enriched Phosphatase
  • PEST-Enriched Phosphatase
  • Phosphatase, PEST-Enriched
  • PTPase, PEP
  • PTP-PEST

Scope note

  • A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of a N-terminal catalytic domain and a large C-terminal domain that is enriched in PROLINE, GLUTAMIC ACID, SERINE, and THREONINE residues (PEST sequences). The phosphatase subtype is ubiquitously expressed and implicated in the regulation of a variety of biological processes such as CELL MOVEMENT; CYTOKINESIS; focal adhesion disassembly; and LYMPHOCYTE ACTIVATION.

History note

  • 2008(1994)

In other languages

URI

http://www.yso.fi/onto/mesh/D054594

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