Skip to main content

Medical Subject Headings

Search from vocabulary

Content language

Concept information

Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > 3',5'-Cyclic-AMP Phosphodiesterases > Cyclic Nucleotide Phosphodiesterases, Type 3
Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > 3',5'-Cyclic-AMP Phosphodiesterases > Cyclic Nucleotide Phosphodiesterases, Type 3
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Esterases > Phosphoric Diester Hydrolases > 3',5'-Cyclic-AMP Phosphodiesterases > Cyclic Nucleotide Phosphodiesterases, Type 3

Preferred term

Cyclic Nucleotide Phosphodiesterases, Type 3  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • cGMP Inhibited Cyclic Nucleotide Phosphodiesterase
  • cGMP-Inhibited Cyclic Nucleotide Phosphodiesterase
  • cGMP Inhibited Phosphodiesterase
  • cGMP-Inhibited Phosphodiesterase
  • Cyclic Nucleotide Phosphodiesterase PDE3 Family
  • Phosphodiesterase, cGMP-Inhibited
  • Phosphodiesterase III

Scope note

  • A cyclic nucleotide phosphodiesterase subfamily that is inhibited by the binding of CYCLIC GMP to an allosteric domain found on the enzyme and through phosphorylation by regulatory kinases such as PROTEIN KINASE A and PROTEIN KINASE B. The two members of this family are referred to as type 3A, and type 3B, and are each product of a distinct gene. In addition multiple enzyme variants of each subtype can be produced due to multiple alternative mRNA splicing.

History note

  • 2008(1995)

In other languages

URI

http://www.yso.fi/onto/mesh/D054684

Download this concept:

RDF/XML TURTLE JSON-LD Created 7/9/07, last modified 5/21/21