Concept information
Amino Acids, Peptides, and Proteins
Proteins
Intracellular Signaling Peptides and Proteins
3',5'-Cyclic-AMP Phosphodiesterases
Preferred term
Cyclic Nucleotide Phosphodiesterases, Type 4
Type
-
Topical Descriptor
Broader concept
Entry terms
- Cyclic Nucleotide Phosphodiesterase PDE4 Family
- PDE4 Phosphodiesterases
- Phosphodiesterase 4
- Phosphodiesterase-4
- Phosphodiesterase IV
- Phosphodiesterases, PDE4
- Type 4 Cyclic Nucleotide Phosphodiesterase
Scope note
- A cyclic nucleotide phosphodiesterase subfamily that is found predominantly in inflammatory cells and may play a role in the regulation of CELL-MEDIATED IMMUNITY. The enzyme family includes over twenty different variants that occur due to multiple ALTERNATIVE SPLICING of the mRNA of at least four different genes.
History note
- 2008(1981)
In other languages
-
Finnish
-
tyypin 4 syklinen nukleotidifosfodiesteraasi
-
Swedish
URI
http://www.yso.fi/onto/mesh/D054703
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