Concept information
Preferred term
PDZ Domains
Type
-
Topical Descriptor
Broader concept
Entry terms
- DHR Domain
- DHR Domains
- DLG Homology Repeats Domains
- Domain, DHR
- Domain, GLGF Repeats
- Domain, PDZ Interaction
- Domain, PSD95-DLG-ZO1
- Domains, DHR
- Domains, GLGF Repeats
- Domains, PDZ Interaction
- Domains, PSD95-DLG-ZO1
- GLGF Repeats Domain
- GLGF Repeats Domains
- Interaction Domain, PDZ
- Interaction Domains, PDZ
- PDZ Interaction Domain
- PDZ Interaction Domains
- PSD95-DLG-ZO1 Domain
- PSD95 DLG ZO1 Domains
- PSD95-DLG-ZO1 Domains
- Repeats Domain, GLGF
- Repeats Domains, GLGF
Scope note
- Protein interaction domains of about 70-90 amino acid residues, named after a common structure found in PSD-95, Discs Large, and Zona Occludens 1 proteins. PDZ domains are involved in the recruitment and interaction of proteins, and aid the formation of protein scaffolds and signaling networks. This is achieved by sequence-specific binding between a PDZ domain in one protein and a PDZ motif in another protein.
History note
- 2008
In other languages
-
Finnish
-
PDZ-domeeni
-
Swedish
-
DHR-domäner
URI
http://www.yso.fi/onto/mesh/D054731
{{label}}
{{#each values }} {{! loop through ConceptPropertyValue objects }}
{{#if prefLabel }}
{{/if}}
{{/each}}
{{#if notation }}{{ notation }} {{/if}}{{ prefLabel }}
{{#ifDifferentLabelLang lang }} ({{ lang }}){{/ifDifferentLabelLang}}
{{#if vocabName }}
{{ vocabName }}
{{/if}}