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... > Enzymes and Coenzymes > Enzymes > Hydrolases > Glycoside Hydrolases > Hexosaminidases > beta-N-Acetylhexosaminidases > Hexosaminidase A

Preferred term

Hexosaminidase A  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Related concepts

Entry terms

  • beta N Acetylhexosaminidase A
  • beta-N-Acetylhexosaminidase A
  • Hex A

Note

  • for deficiency consider: SANDHOFF DISEASE or TAY-SACHS DISEASE

Scope note

  • A mammalian beta-hexosaminidase isoform that is a heteromeric protein comprized of both hexosaminidase alpha and hexosaminidase beta subunits. Deficiency of hexosaminidase A due to mutations in the gene encoding the hexosaminidase alpha subunit is a case of TAY-SACHS DISEASE. Deficiency of hexosaminidase A and HEXOSAMINIDASE B due to mutations in the gene encoding the hexosaminidase beta subunit is a case of SANDHOFF DISEASE.

History note

  • 2008(1987); for HEXOSAMINIDASE A use BETA-N-ACETYLHEXOSAMINIDASE 1987-2007

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URI

http://www.yso.fi/onto/mesh/D054818

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