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... > Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > TGF-beta Superfamily Proteins > Growth Differentiation Factors > Growth Differentiation Factor 1
Biological Factors > Intercellular Signaling Peptides and Proteins > TGF-beta Superfamily Proteins > Growth Differentiation Factors > Growth Differentiation Factor 1
... > Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > TGF-beta Superfamily Proteins > Growth Differentiation Factors > Growth Differentiation Factor 1
... > Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > TGF-beta Superfamily Proteins > Nodal Signaling Ligands > Growth Differentiation Factor 1
Biological Factors > Intercellular Signaling Peptides and Proteins > TGF-beta Superfamily Proteins > Nodal Signaling Ligands > Growth Differentiation Factor 1
... > Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > TGF-beta Superfamily Proteins > Nodal Signaling Ligands > Growth Differentiation Factor 1

Preferred term

Growth Differentiation Factor 1  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • GDF-1

Scope note

  • A growth differentiation factor that plays a role in the genesis of left-right asymmetry during vertebrate development. Evidence for this role is seen in MICE where loss of growth differentiation factor 1 function results in right-left isomerism of visceral organs. In HUMANS heterozygous loss of growth differentiation factor 1 function has been associated with CONGENITAL HEART DEFECTS and TRANSPOSITION OF GREAT VESSELS.

History note

  • 2009(2005)

In other languages

URI

http://www.yso.fi/onto/mesh/D055452

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