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Concept information

Preferred term

Acid Ceramidase  

Type

  • Topical Descriptor

Broader concept

Scope note

  • A ceramidase subtype that is active at acid pH. It plays an important role in sphingolipid degradation by catalyzing the lysosomal hydrolysis of ceramide to sphingosine and free fatty acid. Inherited deficiency of acid ceramidase activity results in FARBER LIPOGRANULOMATOSIS.

History note

  • 2009(1982); use GALACTOSYLGALACTOSYLGLUCOSYLCERAMIDASE 1983-2008

In other languages

URI

http://www.yso.fi/onto/mesh/D055573

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