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Concept information

Preferred term

Nuclear Receptor Co-Repressor 2  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Co-repressor, SMRT
  • Co-repressor, TRAC
  • Receptor-associating Factor, T3
  • Silencing Mediator of Retinoic Acid and Thyroid Hormone Receptor
  • SMRT Co repressor
  • SMRT Co-repressor
  • T3 Receptor associating Factor
  • T3 Receptor-associating Factor
  • TRAC Co repressor
  • TRAC Co-repressor

Scope note

  • A nuclear co-repressor protein that shows specificity for RETINOIC ACID RECEPTORS and THYROID HORMONE RECEPTORS. The dissociation of this co-repressor from nuclear receptors is generally ligand-dependent, but can also occur by way of its phosphorylation by members of the MAP KINASE SIGNALING SYSTEM. The protein contains two nuclear receptor interaction domains and four repressor domains and is closely-related in structure to NUCLEAR RECEPTOR CO-REPRESSOR 1.

History note

  • 2010(1995)

In other languages

URI

http://www.yso.fi/onto/mesh/D056985

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