Concept information
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Proteins
Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Receptor Protein-Tyrosine Kinases
Preferred term
Receptor Tyrosine Kinase-like Orphan Receptors
Type
-
Topical Descriptor
Broader concept
Entry terms
- Neurotrophic Tyrosine Kinase, Receptor related Proteins
- Neurotrophic Tyrosine Kinase, Receptor-related Proteins
- NTRKR Receptors
- Receptor Tyrosine Kinase like Orphan Receptor
- Receptor Tyrosine Kinase-like Orphan Receptor
- ROR Tyrosine Kinase Receptors
Note
- do not confuse with ORPHAN NUCLEAR RECEPTORS
Scope note
- A family of cell surface receptors that were originally identified by their structural homology to neurotropic TYROSINE KINASES and referred to as orphan receptors because the associated ligand and signaling pathways were unknown. Evidence for the functionality of these proteins has been established by experiments showing that disruption of the orphan receptor genes results in developmental defects.
History note
- 2010
In other languages
-
Finnish
-
tyrosiinikinaasireseptorien kaltaiset orporeseptorit
-
Swedish
URI
http://www.yso.fi/onto/mesh/D057050
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