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Concept information

Preferred term

Receptor Tyrosine Kinase-like Orphan Receptors  

Type

  • Topical Descriptor

Entry terms

  • Neurotrophic Tyrosine Kinase, Receptor related Proteins
  • Neurotrophic Tyrosine Kinase, Receptor-related Proteins
  • NTRKR Receptors
  • Receptor Tyrosine Kinase like Orphan Receptor
  • Receptor Tyrosine Kinase-like Orphan Receptor
  • ROR Tyrosine Kinase Receptors

Note

  • do not confuse with ORPHAN NUCLEAR RECEPTORS

Scope note

  • A family of cell surface receptors that were originally identified by their structural homology to neurotropic TYROSINE KINASES and referred to as orphan receptors because the associated ligand and signaling pathways were unknown. Evidence for the functionality of these proteins has been established by experiments showing that disruption of the orphan receptor genes results in developmental defects.

History note

  • 2010

In other languages

URI

http://www.yso.fi/onto/mesh/D057050

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