Concept information
Preferred term
DAX-1 Orphan Nuclear Receptor
Type
-
Topical Descriptor
Broader concept
Entry terms
- DSS AHC Critical Region on the X Chromosome, Gene 1 Protein
- DSS-AHC Critical Region on the X Chromosome, Gene 1 Protein
- NR0B1 Protein
- Nuclear Receptor 0B1
- Nuclear Receptor DAX 1
- Nuclear Receptor DAX-1
- Nuclear Receptor NR0B1
- Nuclear Receptor Subfamily 0, Group B, Member 1
Scope note
- An orphan nuclear receptor that is implicated in regulation of steroidogenic pathways. It is unlike most orphan nuclear receptors in that it appears to lack an essential DNA-binding domain and instead acts as a transcriptional co-repressor. Mutations in the gene Dax-1 cause congenital adrenal hypoplasia.
History note
- 2010(1995)
In other languages
-
Finnish
-
DAX-1 orphan nuclear receptor
-
Swedish
URI
http://www.yso.fi/onto/mesh/D057137
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