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Concept information

Preferred term

DAX-1 Orphan Nuclear Receptor  

Type

  • Topical Descriptor

Entry terms

  • DSS AHC Critical Region on the X Chromosome, Gene 1 Protein
  • DSS-AHC Critical Region on the X Chromosome, Gene 1 Protein
  • NR0B1 Protein
  • Nuclear Receptor 0B1
  • Nuclear Receptor DAX 1
  • Nuclear Receptor DAX-1
  • Nuclear Receptor NR0B1
  • Nuclear Receptor Subfamily 0, Group B, Member 1

Scope note

  • An orphan nuclear receptor that is implicated in regulation of steroidogenic pathways. It is unlike most orphan nuclear receptors in that it appears to lack an essential DNA-binding domain and instead acts as a transcriptional co-repressor. Mutations in the gene Dax-1 cause congenital adrenal hypoplasia.

History note

  • 2010(1995)

In other languages

URI

http://www.yso.fi/onto/mesh/D057137

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