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Mental Disorders > Neurocognitive Disorders > Dementia > Frontotemporal Lobar Degeneration
Nervous System Diseases > Central Nervous System Diseases > Brain Diseases > Dementia > Frontotemporal Lobar Degeneration
Nervous System Diseases > Neurodegenerative Diseases > TDP-43 Proteinopathies > Frontotemporal Lobar Degeneration
Nutritional and Metabolic Diseases > Metabolic Diseases > Proteostasis Deficiencies > TDP-43 Proteinopathies > Frontotemporal Lobar Degeneration

Preferred term

Frontotemporal Lobar Degeneration  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • FTLD
  • FTLDs

Scope note

  • Heterogeneous group of neurodegenerative disorders characterized by frontal and temporal lobe atrophy associated with neuronal loss, gliosis, and dementia. Patients exhibit progressive changes in social, behavioral, and/or language function. Multiple subtypes or forms are recognized based on presence or absence of TAU PROTEIN inclusions. FTLD includes three clinical syndromes: FRONTOTEMPORAL DEMENTIA, semantic dementia, and PRIMARY PROGRESSIVE NONFLUENT APHASIA.

History note

  • 2010; use DEMENTIA 2000-2009; for SEMANTIC DEMENTIA use DEMENTIA 2000-2009

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URI

http://www.yso.fi/onto/mesh/D057174

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