Concept information
Preferred term
Telomere Shortening
Type
-
Topical Descriptor
Broader concept
Scope note
- The loss of some TELOMERE sequence during DNA REPLICATION of the first several base pairs of a linear DNA molecule; or from DNA DAMAGE. Cells have various mechanisms to restore length (TELOMERE HOMEOSTASIS.) Telomere shortening is involved in the progression of CELL AGING.
History note
- 2012
In other languages
-
Finnish
-
telomeerin lyheneminen
-
Swedish
URI
http://www.yso.fi/onto/mesh/D059506
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