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Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Axin Signaling Complex
Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Axin Signaling Complex
Macromolecular Substances > Multiprotein Complexes > Axin Signaling Complex

Preferred term

Axin Signaling Complex  

Type

  • Topical Descriptor

Broader concept

Narrower concepts

Entry terms

  • Axin Signaling Complex Proteins
  • beta Catenin Destruction Complex
  • beta-Catenin Destruction Complex
  • Destruction Complex, beta-Catenin

Scope note

  • A specific complex of WNT SIGNALING PATHWAY proteins that mediates the phosphorylation-dependent destruction of cytosolic BETA-CATENIN. The complex is disrupted by cell surface binding of WNT PROTEINS, which allows beta-catenin levels to rise to the point where they migrate to the CELL NUCLEUS and activate transcription.

History note

  • 2012

In other languages

URI

http://www.yso.fi/onto/mesh/D060465

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