Concept information
...
Gene Expression Regulation
Protein Modification, Translational
Protein Processing, Post-Translational
Unfolded Protein Response
...
Protein Biosynthesis
Protein Modification, Translational
Protein Processing, Post-Translational
Unfolded Protein Response
Preferred term
Endoplasmic Reticulum-Associated Degradation
Type
-
Topical Descriptor
Broader concept
Entry terms
- ERAD Pathway
- ERAD Pathways
- Pathway, ERAD
- Pathways, ERAD
Scope note
- A degradation process whereby incorrectly folded proteins are selectively transported out of the ENDOPLASMIC RETICULUM and into the CYTOSOL. The misfolded proteins are subsequently ubiquitinated and degraded by the PROTEASOME.
History note
- 2012
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D060746
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