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Concept information

Preferred term

Endoplasmic Reticulum-Associated Degradation  

Type

  • Topical Descriptor

Entry terms

  • ERAD Pathway
  • ERAD Pathways
  • Pathway, ERAD
  • Pathways, ERAD

Scope note

  • A degradation process whereby incorrectly folded proteins are selectively transported out of the ENDOPLASMIC RETICULUM and into the CYTOSOL. The misfolded proteins are subsequently ubiquitinated and degraded by the PROTEASOME.

History note

  • 2012

In other languages

URI

http://www.yso.fi/onto/mesh/D060746

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