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Concept information

Preferred term

B7-H1 Antigen  

Type

  • Topical Descriptor

Entry terms

  • Antigen, CD274
  • Antigens, CD274
  • B7 H1 Immune Costimulatory Protein
  • B7-H1 Immune Costimulatory Protein
  • B7H1 Immune Costimulatory Protein
  • CD274 Antigen
  • CD274 Antigens
  • Costimulatory Protein, PD-L1
  • PD L1 Costimulatory Protein
  • PD-L1 Costimulatory Protein
  • PD L1 Protein
  • PD-L1 Protein
  • Programmed Cell Death 1 Ligand 1
  • Programmed Cell Death 1 Ligand 1 Protein
  • Programmed Death Ligand 1

Scope note

  • An inhibitory B7 antigen that contains V-type and C2 type immunoglobulin domains. It has specificity for the T-CELL receptor PROGRAMMED CELL DEATH 1 PROTEIN and provides negative signals that control and inhibit T-cell responses. It is found at higher than normal levels on tumor cells, suggesting its potential role in TUMOR IMMUNE EVASION.

History note

  • 2018 (2007)

In other languages

URI

http://www.yso.fi/onto/mesh/D060890

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