Concept information
Amino Acids, Peptides, and Proteins
Proteins
Intercellular Signaling Peptides and Proteins
B7 Antigens
Preferred term
B7-H1 Antigen
Type
-
Topical Descriptor
Broader concept
Entry terms
- Antigen, CD274
- Antigens, CD274
- B7 H1 Immune Costimulatory Protein
- B7-H1 Immune Costimulatory Protein
- B7H1 Immune Costimulatory Protein
- CD274 Antigen
- CD274 Antigens
- Costimulatory Protein, PD-L1
- PD L1 Costimulatory Protein
- PD-L1 Costimulatory Protein
- PD L1 Protein
- PD-L1 Protein
- Programmed Cell Death 1 Ligand 1
- Programmed Cell Death 1 Ligand 1 Protein
- Programmed Death Ligand 1
Scope note
- An inhibitory B7 antigen that contains V-type and C2 type immunoglobulin domains. It has specificity for the T-CELL receptor PROGRAMMED CELL DEATH 1 PROTEIN and provides negative signals that control and inhibit T-cell responses. It is found at higher than normal levels on tumor cells, suggesting its potential role in TUMOR IMMUNE EVASION.
History note
- 2018 (2007)
In other languages
-
Finnish
-
CD274-antigeeni
-
CD274-antigeenit
-
Swedish
-
Antigener, CD274
-
CD274-antigener
URI
http://www.yso.fi/onto/mesh/D060890
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