Concept information
Preferred term
Programmed Cell Death 1 Receptor
Type
-
Topical Descriptor
Broader concept
Entry terms
- Antigen, CD279
- Antigens, CD279
- CD279 Antigen
- CD279 Antigens
- PD 1 Protein
- PD-1 Protein
- PD 1 Receptor
- PD-1 Receptor
- PD1 Receptor
- Programmed Cell Death 1 Protein
- Programmed Cell Death Protein 1
- Receptor, PD-1
- Receptor, PD1
Scope note
- An inhibitory T-lymphocyte receptor that has specificity for CD274 ANTIGEN and PROGRAMMED CELL DEATH 1 LIGAND 2 PROTEIN. Signaling by the receptor limits T cell proliferation and INTERFERON GAMMA synthesis. The receptor also may play an essential role in the regulatory pathway that induces PERIPHERAL TOLERANCE.
History note
- 2012
In other languages
-
Finnish
-
Swedish
URI
http://www.yso.fi/onto/mesh/D061026
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