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Concept information

Preferred term

Programmed Cell Death 1 Receptor  

Type

  • Topical Descriptor

Entry terms

  • Antigen, CD279
  • Antigens, CD279
  • CD279 Antigen
  • CD279 Antigens
  • PD 1 Protein
  • PD-1 Protein
  • PD 1 Receptor
  • PD-1 Receptor
  • PD1 Receptor
  • Programmed Cell Death 1 Protein
  • Programmed Cell Death Protein 1
  • Receptor, PD-1
  • Receptor, PD1

Scope note

  • An inhibitory T-lymphocyte receptor that has specificity for CD274 ANTIGEN and PROGRAMMED CELL DEATH 1 LIGAND 2 PROTEIN. Signaling by the receptor limits T cell proliferation and INTERFERON GAMMA synthesis. The receptor also may play an essential role in the regulatory pathway that induces PERIPHERAL TOLERANCE.

History note

  • 2012

In other languages

URI

http://www.yso.fi/onto/mesh/D061026

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