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Immune System Phenomena > Immunomodulation > Immune Tolerance > Self Tolerance > Central Tolerance
... > Therapeutics > Biological Therapy > Immunomodulation > Immune Tolerance > Self Tolerance > Central Tolerance

Preferred term

Central Tolerance  

Type

  • Topical Descriptor

Broader concept

Scope note

  • The mechanism, in central lymphoid organs (THYMUS; BONE MARROW), that prevents immature lymphocytes from reacting to SELF-ANTIGENS. This is accomplished by CLONAL ANERGY and CLONAL DELETION.

History note

  • 2012

In other languages

URI

http://www.yso.fi/onto/mesh/D061167

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