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... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Protein Conformation > Protein Structural Elements > Amino Acid Motifs > Immunoreceptor Tyrosine-Based Inhibition Motif
... > Chemical Phenomena > Biochemical Phenomena > Molecular Structure > Molecular Conformation > Protein Conformation > Protein Structure, Secondary > Amino Acid Motifs > Immunoreceptor Tyrosine-Based Inhibition Motif

Preferred term

Immunoreceptor Tyrosine-Based Inhibition Motif  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Immune Receptor Tyrosine Based Inhibition Motif
  • Immune Receptor Tyrosine-Based Inhibition Motif
  • Immuno Receptor Tyrosine Based Inhibition Motif
  • Immuno-Receptor Tyrosine-Based Inhibition Motif

Scope note

  • A conserved AMINO ACID SEQUENCE located in the intracellular domains of a family of transmembrane proteins that negatively regulate the signal transduction processes emanating from transmembrane proteins containing IMMUNORECEPTOR TYROSINE-BASED ACTIVATION MOTIFS. The CONSENSUS SEQUENCE of this motif is I(or V)LXYXXL(or V) (where X denotes any amino acid). Also known as ITIM motifs.

History note

  • 2013

In other languages

URI

http://www.yso.fi/onto/mesh/D061626

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