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... > Amino Acids, Peptides, and Proteins > Proteins > Membrane Proteins > Tight Junction Proteins > Claudins > Claudin-1

Preferred term

Claudin-1  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Claudin 1

Scope note

  • An integral membrane protein that is localized to TIGHT JUNCTIONS, where it plays a role in controlling the paracellular permeability of polarized cells. Mutations in the gene for claudin-1 are associated with Neonatal Ichthyosis-Sclerosing Cholangitis (NISCH) Syndrome.

History note

  • 2013

In other languages

URI

http://www.yso.fi/onto/mesh/D062445

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