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Concept information

Preferred term

Voltage-Gated Sodium Channel beta-1 Subunit  

Type

  • Topical Descriptor

Entry terms

  • SCN1B Sodium Channel beta Subunit

Scope note

  • A voltage-gated sodium channel beta subunit abundantly expressed in SKELETAL MUSCLE; HEART; and BRAIN. It non-covalently associates with voltage-gated alpha subunits. Defects in the SCN1B gene, which codes for this beta subunit, are associated with generalized epilepsy with febrile seizures plus, type 1, and Brugada syndrome 5.

History note

  • 2013

URI

http://www.yso.fi/onto/mesh/D062547

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