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Concept information

Preferred term

NAV1.1 Voltage-Gated Sodium Channel  

Type

  • Topical Descriptor

Entry terms

  • Type 1 Voltage Gated Sodium Channel
  • Type 1 Voltage-Gated Sodium Channel
  • Voltage Gated Sodium Channel Type 1
  • Voltage-Gated Sodium Channel Type 1

Scope note

  • A voltage-gated sodium channel subtype that is predominantly expressed in the CENTRAL NERVOUS SYSTEM. Defects in the SCN1A gene which codes for the alpha subunit of this sodium channel are associated with DRAVET SYNDROME, generalized epilepsy with febrile seizures plus, type 2 (GEFS+2), and familial hemiplegic migraine type 3.

History note

  • 2013

In other languages

URI

http://www.yso.fi/onto/mesh/D062550

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