Concept information
Preferred term
Sialic Acid Binding Ig-like Lectin 3
Type
-
Topical Descriptor
Broader concept
Entry terms
- Antigen, CD33
- Antigens, CD33
- CD33 Antigen
- CD33 Antigens
- Glycoprotein gp67
- gp67, Glycoprotein
- Siglec-3
Scope note
- A 67-kDa sialic acid binding lectin that is specific for MYELOID CELLS and MONOCYTE-MACROPHAGE PRECURSOR CELLS. This protein is the smallest siglec subtype and contains a single immunoglobulin C2-set domain. It may play a role in intracellular signaling via its interaction with SHP-1 PROTEIN-TYROSINE PHOSPHATASE and SHP-2 PROTEIN-TYROSINE PHOSPHATASE.
History note
- 2013
In other languages
URI
http://www.yso.fi/onto/mesh/D063268
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