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Concept information

Preferred term

Sialic Acid Binding Ig-like Lectin 3  

Type

  • Topical Descriptor

Entry terms

  • Antigen, CD33
  • Antigens, CD33
  • CD33 Antigen
  • CD33 Antigens
  • Glycoprotein gp67
  • gp67, Glycoprotein
  • Siglec-3

Scope note

  • A 67-kDa sialic acid binding lectin that is specific for MYELOID CELLS and MONOCYTE-MACROPHAGE PRECURSOR CELLS. This protein is the smallest siglec subtype and contains a single immunoglobulin C2-set domain. It may play a role in intracellular signaling via its interaction with SHP-1 PROTEIN-TYROSINE PHOSPHATASE and SHP-2 PROTEIN-TYROSINE PHOSPHATASE.

History note

  • 2013

URI

http://www.yso.fi/onto/mesh/D063268

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