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Concept information

Preferred term

Ataxia Telangiectasia Mutated Proteins  

Type

  • Topical Descriptor

Entry terms

  • ATM Protein
  • AT Mutated Protein
  • A T Protein
  • A-T Protein
  • Mutated Protein, AT
  • Protein, A-T
  • Protein, AT Mutated

Scope note

  • A group of PROTEIN SERINE-THREONINE KINASES which activate critical signaling cascades in double strand breaks, APOPTOSIS, and GENOTOXIC STRESS such as ionizing ultraviolet A light, thereby acting as a DNA damage sensor. These proteins play a role in a wide range of signaling mechanisms in cell cycle control.

History note

  • 2014

In other languages

  • Finnish

  • ataksia-telangiektasiassa muuttuneet proteiinit

URI

http://www.yso.fi/onto/mesh/D064007

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