Concept information
Amino Acids, Peptides, and Proteins
Proteins
Intracellular Signaling Peptides and Proteins
Protein Serine-Threonine Kinases
Amino Acids, Peptides, and Proteins
Peptides
Intracellular Signaling Peptides and Proteins
Protein Serine-Threonine Kinases
Preferred term
Ataxia Telangiectasia Mutated Proteins
Type
-
Topical Descriptor
Broader concept
Entry terms
- ATM Protein
- AT Mutated Protein
- A T Protein
- A-T Protein
- Mutated Protein, AT
- Protein, A-T
- Protein, AT Mutated
Scope note
- A group of PROTEIN SERINE-THREONINE KINASES which activate critical signaling cascades in double strand breaks, APOPTOSIS, and GENOTOXIC STRESS such as ionizing ultraviolet A light, thereby acting as a DNA damage sensor. These proteins play a role in a wide range of signaling mechanisms in cell cycle control.
History note
- 2014
In other languages
-
Finnish
-
ataksia-telangiektasiassa muuttuneet proteiinit
URI
http://www.yso.fi/onto/mesh/D064007
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