Concept information
Preferred term
Rho Guanine Nucleotide Exchange Factors
Type
-
Topical Descriptor
Broader concept
Narrower concepts
Entry terms
- Rho Guanine Nucleotide Exchange Factor 6
- Rho Guanine Nucleotide Exchange Factor 7
- Rho Guanine Nucleotide Exchange Factor p115
Scope note
- Signaling proteins which function as master molecular switches by activating Rho GTPases through conversion of guanine nucleotides. Rho GTPases in turn control many aspects of cell behavior through the regulation of multiple downstream signal transduction pathways.
History note
- 2014
In other languages
-
Finnish
-
rho guanine nucleotide exchange factors
-
rhoGEFs
URI
http://www.yso.fi/onto/mesh/D064067
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