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Concept information

Preferred term

Apc3 Subunit, Anaphase-Promoting Complex-Cyclosome  

Type

  • Topical Descriptor

Entry terms

  • Anapc3
  • Apc3 Subunit, Anaphase Promoting Complex
  • Apc3 Subunit, Anaphase-Promoting Complex
  • CDC27 Protein

Scope note

  • A highly evolutionarily conserved subunit of the anaphase-promoting complex (APC-C) containing multiple 34-amino-acid tetratricopeptide repeats. These domains, also found in Apc subunits 6, 7, and 8, have been shown to mediate protein-protein interactions, suggesting that Apc3 may assist in coordinating the juxtaposition of the catalytic and substrate recognition module subunits relative to co-activators and APC-C inhibitors.

History note

  • 2014

In other languages

URI

http://www.yso.fi/onto/mesh/D064191

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