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Concept information

Preferred term

Apc8 Subunit, Anaphase-Promoting Complex-Cyclosome  

Type

  • Topical Descriptor

Entry terms

  • Anapc8
  • Apc8 Subunit, Anaphase Promoting Complex
  • Apc8 Subunit, Anaphase-Promoting Complex

Scope note

  • A highly conserved subunit of the anaphase-promoting complex (APC-C) containing multiple 34-amino-acid tetratricopeptide repeats. These domains, also found in Apc3, Apc6, and Apc7, have been shown to mediate protein-protein interactions, suggesting that Apc8 may assist in coordinating the juxtaposition of the catalytic and substrate recognition module subunits relative to coactivators and APC-C inhibitors.

History note

  • 2014

In other languages

URI

http://www.yso.fi/onto/mesh/D064196

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