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Amino Acids, Peptides, and Proteins > Proteins > Nuclear Proteins > Mad2 Proteins
Amino Acids, Peptides, and Proteins > Proteins > Cell Cycle Proteins > Mad2 Proteins

Preferred term

Mad2 Proteins  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Mad2 Mitotic Arrest Deficient-like 1 Proteins

Scope note

  • Mad2 is a component of the spindle-assembly checkpoint apparatus. It binds to and inhibits the Cdc20 activator subunit of the anaphase-promoting complex, preventing the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Mad2 is required for proper microtubule capture at KINETOCHORES.

History note

  • 2014

In other languages

URI

http://www.yso.fi/onto/mesh/D064246

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