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Concept information

Amino Acids, Peptides, and Proteins > Proteins > Cell Cycle Proteins > Geminin

Preferred term

Geminin  

Type

  • Topical Descriptor

Broader concept

Scope note

  • Geminin inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex. It is absent during G1 phase of the CELL CYCLE and accumulates through S, G2,and M phases. It is degraded at the metaphase-anaphase transition by the ANAPHASE-PROMOTING COMPLEX-CYCLOSOME.

History note

  • 2014

In other languages

URI

http://www.yso.fi/onto/mesh/D064248

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