Concept information
Preferred term
Spike Glycoprotein, Coronavirus
Type
-
Topical Descriptor
Broader concept
Entry terms
- Coronavirus Spike Protein
- Glycoprotein S, Coronavirus
- Spike Glycoproteins, Coronavirus
- Spike Protein, Coronavirus
Scope note
- A class I viral fusion protein that forms the characteristic spikes, or peplomers, found on the viral surface that mediate virus attachment, fusion, and entry into the host cell. During virus maturation, it is cleaved into two subunits: S1, which binds to receptors in the host cell, and S2, which mediates membrane fusion.
History note
- 2014
In other languages
URI
http://www.yso.fi/onto/mesh/D064370
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