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Amino Acids, Peptides, and Proteins > Proteins > Contractile Proteins > Filamins
... > Chemical Actions and Uses > Specialty Uses of Chemicals > Biomedical and Dental Materials > Polymers > Biopolymers > Microfilament Proteins > Filamins
... > Technology, Industry, and Agriculture > Manufactured Materials > Biomedical and Dental Materials > Polymers > Biopolymers > Microfilament Proteins > Filamins
Macromolecular Substances > Polymers > Biopolymers > Microfilament Proteins > Filamins
Amino Acids, Peptides, and Proteins > Proteins > Cytoskeletal Proteins > Microfilament Proteins > Filamins
... > Fluids and Secretions > Body Fluids > Body Fluid Compartments > Intracellular Space > Cytoplasm > Cytoplasmic Structures > Cytoskeleton > Actin Cytoskeleton > Filamins
... > Tissues > Body Fluid Compartments > Intracellular Space > Cytoplasm > Cytoplasmic Structures > Cytoskeleton > Actin Cytoskeleton > Filamins
... > Cells > Cellular Structures > Intracellular Space > Cytoplasm > Cytoplasmic Structures > Cytoskeleton > Actin Cytoskeleton > Filamins

Preferred term

Filamins  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Filamin

Scope note

  • A family of crosslinking filament proteins encoded by distinct FLN genes. Filamins are involved in cell adhesion, spreading, and migration, acting as scaffolds for over 90 binding partners including channels, receptors, intracellular signaling molecules and transcription factors. Due to the range of molecular interactions, mutations in FLN genes result in anomalies with moderate to lethal consequences.

History note

  • 2014

In other languages

URI

http://www.yso.fi/onto/mesh/D064448

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