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Concept information

Preferred term

Solute Carrier Family 12, Member 1  

Type

  • Topical Descriptor

Entry terms

  • BSC1 Transport Protein
  • Bumetanide-Sensitive Sodium-(Potassium)-Chloride Cotransporter 2
  • Cotransporter, NKCC2
  • Cotransporter, SLC12A1
  • Kidney Specific Na K Cl Symporter
  • Kidney-Specific Na-K-Cl Symporter
  • Na-K-Cl Symporter, Kidney-Specific
  • NKCC2 Cotransporter
  • NKCC2 Protein
  • Protein, BSC1 Transport
  • Protein, NKCC2
  • Protein, SLC12A1
  • SLC12A1 Cotransporter
  • SLC12A1 Protein
  • Symporter, Kidney-Specific Na-K-Cl
  • Transport Protein, BSC1

Scope note

  • Na-K-Cl transporter in the ASCENDING LIMB OF LOOP OF HENLE. It mediates active reabsorption of sodium chloride and is inhibited by LOOP DIURETICS such as FUROSEMIDE; and BUMETANIDE. Mutations in the gene encoding SLC12A1 are associated with a BARTTER SYNDROME.

History note

  • 2014

In other languages

URI

http://www.yso.fi/onto/mesh/D064466

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