Concept information
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Proteins
Intracellular Signaling Peptides and Proteins
Apoptosis Regulatory Proteins
Proto-Oncogene Proteins c-bcl-2
Preferred term
Myeloid Cell Leukemia Sequence 1 Protein
Type
-
Topical Descriptor
Broader concept
Entry terms
- Cell Factor-1, Myeloid
- Factor-1, Myeloid Cell
- Induced Myeloid Leukemia Cell Differentiation Protein Mcl 1
- Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1
- Myeloid Cell Factor 1
- Myeloid Cell Factor-1
- Myeloid Cell Leukemia Sequence 1
Scope note
- A member of the myeloid leukemia factor (MLF) protein family with multiple alternatively spliced transcript variants encoding different protein isoforms. In hematopoietic cells, it is located mainly in the nucleus, and in non-hematopoietic cells, primarily in the cytoplasm with a punctate nuclear localization. MLF1 plays a role in cell cycle differentiation.
History note
- 2014
In other languages
URI
http://www.yso.fi/onto/mesh/D064549
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