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Pathological Conditions, Signs and Symptoms > Pathologic Processes > Protein Aggregation, Pathological
Chemical Phenomena > Biochemical Phenomena > Protein Aggregation, Pathological

Preferred term

Protein Aggregation, Pathological  

Type

  • Topical Descriptor

Broader concept

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Scope note

  • A biochemical phenomenon in which misfolded proteins aggregate either intra- or extracellularly. Triggered by factors such as MUTATION; POST-TRANSLATIONAL MODIFICATIONS, and environmental stress, it is generally associated with ALZHEIMER DISEASE; PARKINSON DISEASE; HUNTINGTON DISEASE; and TYPE 2 DIABETES MELLITUS.

History note

  • 2015

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URI

http://www.yso.fi/onto/mesh/D066263

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