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Concept information

Preferred term

Abatacept  

Type

  • Topical Descriptor

Broader concept

Entry terms

  • Belatacept
  • BMS 188667
  • BMS224818
  • CTLA-4-Ig
  • LEA29Y
  • Nulojix
  • Orencia

Scope note

  • A fusion protein immunoconjugate of the extracellular domain of CTLA4 and the Fc domain of human IgG1. It functions as a T-cell co-stimulation blocker that inhibits TNF-ALPHA and prevents the activation of T-LYMPHOCYTES. It is used in the treatment of RHEUMATOID ARTHRITIS.

History note

  • 2016 (2002)

In other languages

URI

http://www.yso.fi/onto/mesh/D000069594

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