Käsitteen tiedot
Käytettävä termi
Discoidin Domain
Tyyppi
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Topical Descriptor
Yläkäsite
Ohjaustermit
- Discoidin Domains
Käyttöhuomautus
- A protein domain originally identified in DISCOIDINS. It occurs in a variety of unrelated proteins in multicellular organisms, where it recognizes different ligands with distinct biological functions. Structurally, it consists of two antiparallel beta sheets that form a "jellyroll" configuration stabilized by two intramolecular disulfide bonds. Sequence differences within this module determine ligand specificity; in DISCOIDIN DOMAIN RECEPTORS, it binds to FIBRILLAR COLLAGENS and NON-FIBRILLAR COLLAGENS.
Huomautus muutoshistoriasta
- 2017
Muunkieliset termit
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ruotsi
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suomi
URI
http://www.yso.fi/onto/mesh/D000070822
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