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Medical Subject Headings

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Käsitteen tiedot

Amino Acids, Peptides, and Proteins > Proteins > Lipoproteins > Apolipoproteins > Apolipoproteins E
Lipids > Lipoproteins > Apolipoproteins > Apolipoproteins E
Amino Acids, Peptides, and Proteins > Proteins > Apoproteins > Apolipoproteins > Apolipoproteins E

Käytettävä termi

Apolipoproteins E  

Tyyppi

  • Topical Descriptor

Yläkäsite

Alakäsitteet

Assosiatiiviset käsitteet

Ohjaustermit

  • Apo E
  • Apo-E
  • ApoE

Käyttöhuomautus

  • A class of protein components which can be found in several lipoproteins including HIGH-DENSITY LIPOPROTEINS; VERY-LOW-DENSITY LIPOPROTEINS; and CHYLOMICRONS. Synthesized in most organs, Apo E is important in the global transport of lipids and cholesterol throughout the body. Apo E is also a ligand for LDL receptors (RECEPTORS, LDL) that mediates the binding, internalization, and catabolism of lipoprotein particles in cells. There are several allelic isoforms (such as E2, E3, and E4). Deficiency or defects in Apo E are causes of HYPERLIPOPROTEINEMIA TYPE III.

Huomautus muutoshistoriasta

  • 1985; for APOLIPOPROTEIN E ISOPROTEINS use APOLIPOPROTEINS E 1985-2006 & use APOLIPOPROTEINS 1983-1984

Muunkieliset termit

URI

http://www.yso.fi/onto/mesh/D001057

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RDF/XML TURTLE JSON-LD Luotu 25.5.1984, viimeksi muokattu 5.7.2006