Hyppää sisältöön

Medical Subject Headings

Hae sanastosta

Sisällön kieli

Käsitteen tiedot

Biological Factors > Blood Coagulation Factors > Factor XII
Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Blood Coagulation Factors > Factor XII
Enzymes and Coenzymes > Enzyme Precursors > Factor XII
Amino Acids, Peptides, and Proteins > Proteins > Protein Precursors > Enzyme Precursors > Factor XII

Käytettävä termi

Factor XII  

Tyyppi

  • Topical Descriptor

Yläkäsite

Alakäsitteet

Assosiatiiviset käsitteet

Ohjaustermit

  • Coagulation Factor XII
  • Factor 12
  • Factor Twelve
  • Hageman Factor

Käyttöhuomautus

  • Stable blood coagulation factor activated by contact with the subendothelial surface of an injured vessel. Along with prekallikrein, it serves as the contact factor that initiates the intrinsic pathway of blood coagulation. Kallikrein activates factor XII to XIIa. Deficiency of factor XII, also called the Hageman trait, leads to increased incidence of thromboembolic disease. Mutations in the gene for factor XII that appear to increase factor XII amidolytic activity are associated with HEREDITARY ANGIOEDEMA TYPE III.

Huomautus muutoshistoriasta

  • 66(64)

Muunkieliset termit

URI

http://www.yso.fi/onto/mesh/D005174

Lataa tämä käsite:

RDF/XML TURTLE JSON-LD Luotu 1.1.1999, viimeksi muokattu 30.5.2019