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Immune System Diseases > Autoimmune Diseases > Polyendocrinopathies, Autoimmune
Endocrine System Diseases > Polyendocrinopathies, Autoimmune

Käytettävä termi

Polyendocrinopathies, Autoimmune  

Tyyppi

  • Topical Descriptor

Ohjaustermit

  • Polyglandular Type I Autoimmune Syndrome
  • Polyglandular Type II Autoimmune Syndrome
  • Polyglandular Type III Autoimmune Syndrome

Huomautus

  • do not coordinate with specific endocrine disease term or CANDIDIASIS unless particularly discussed

Käyttöhuomautus

  • Autoimmune diseases affecting multiple endocrine organs. Type I is characterized by childhood onset and chronic mucocutaneous candidiasis (CANDIDIASIS, CHRONIC MUCOCUTANEOUS), while type II exhibits any combination of adrenal insufficiency (ADDISON'S DISEASE), lymphocytic thyroiditis (THYROIDITIS, AUTOIMMUNE;), HYPOPARATHYROIDISM; and gonadal failure. In both types organ-specific ANTIBODIES against a variety of ENDOCRINE GLANDS have been detected. The type II syndrome differs from type I in that it is associated with HLA-A1 and B8 haplotypes, onset is usually in adulthood, and candidiasis is not present.

Huomautus muutoshistoriasta

  • 1992

URI

http://www.yso.fi/onto/mesh/D016884

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