Käsitteen tiedot
Käytettävä termi
Mice, Inbred MRL lpr
Tyyppi
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Topical Descriptor
Yläkäsite
Ohjaustermit
- Mice, MRL lpr
- Mouse, Inbred MRL lpr
- Mouse, MRL lpr
- MRL lpr Mice
- MRL lpr Mouse
Huomautus
- NIM with no qualifiers when experimental animal
Käyttöhuomautus
- A mouse substrain that is genetically predisposed to the development of systemic lupus erythematosus-like syndrome, which has been found to be clinically similar to the human disease. It has been determined that this mouse strain carries a mutation in the fas gene. Also, the MRL/lpr is a useful model to study behavioral and cognitive deficits found in autoimmune diseases and the efficacy of immunosuppressive agents.
Huomautus muutoshistoriasta
- 97
Muunkieliset termit
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ruotsi
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suomi
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sisäsiittoinen MRL lpr -hiiri
URI
http://www.yso.fi/onto/mesh/D019463
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