Käsitteen tiedot
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Carrier Proteins
RNA-Binding Proteins
RNA Recognition Motif Proteins
Heterogeneous-Nuclear Ribonucleoproteins
...
Nucleoproteins
RNA-Binding Proteins
RNA Recognition Motif Proteins
Heterogeneous-Nuclear Ribonucleoproteins
Käytettävä termi
RNA-Binding Protein EWS
Tyyppi
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Topical Descriptor
Yläkäsite
Ohjaustermit
- Ewing Sarcoma Breakpoint Region 1 Protein
- Ewing Sarcoma Breakpointregion 1 Protein
- EWS Protein
- EWS Proto Oncogene Protein
- EWS Proto-Oncogene Protein
- EWSR1 Protein
- EWS RNA Binding Protein 1
- Protein, EWSR1
- Proto-Oncogene Protein, EWS
Käyttöhuomautus
- A ubiquitous hnRNP protein that contains an RNA RECOGNITION MOTIF and C-terminal ranBP2-type zinc finger. It localizes to the CELL NUCLEUS and CYTOPLASM and is expressed as different isoforms in various tissues, interacting with CALMODULIN and TUMOR SUPPRESSOR PROTEIN P53 to negatively regulate cell growth. Translocations that result in the formation of fusion proteins containing parts of RNA-binding protein EWS are associated with EWING SARCOMA.
Huomautus muutoshistoriasta
- 2003; for EWS PROTEIN use HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEINS 1995-2002
Muunkieliset termit
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ruotsi
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suomi
URI
http://www.yso.fi/onto/mesh/D034802
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