Diehtu doahpagis
Amino Acids, Peptides, and Proteins
Proteins
Intracellular Signaling Peptides and Proteins
Apoptosis Regulatory Proteins
Ávžžuhuvvon tearbma
DCC Receptor
Tiipa
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Topical Descriptor
Stivrentearpmat
- DCC Netrin 1 Receptor
- DCC-Netrin-1 Receptor
- DCC Tumor Suppressor Protein
- Deleted in Colorectal Carcinoma Protein
- Receptor, DCC-Netrin-1
Fuomášahttin
- A receptor for NETRIN-1 that contains four membrane distal (N-terminal) Ig-like C2 domains and six membrane proximal (C-terminal) fibronectin type III domains. It is expressed primarily in the nerve axons and differentiated intestinal cells and is required for AXON GUIDANCE, mediating axon attraction of neuronal GROWTH CONES; however, it may also trigger axon repulsion through association with the UNC5 netrin-1 receptor. DCC also induces APOPTOSIS when it is unbound from netrin-1. Deletions of the DCC gene are observed in tumor metastases and the protein is not expressed in undifferentiated COLORECTAL CARCINOMA cells.
Fuomášahttin rievdadanhistorjjás
- 2018
Eará gielain
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Finnish
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DCC-reseptorit
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Swedish
URI
http://www.yso.fi/onto/mesh/D000075389
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